Changes in antibiotic use associated with the National Centralized Drug Procurement policy in China from 2019 to 2023.

ABSTRACT: This study used prescription data from four medical institutions in representative cities in Central, Western and Eastern China, focusing on changes in antibiotic use under the National Centralized Drug Procurement Policy (NCDP) and calculating the contribution of NCDP and non-NCDP varieties to the changes. In outpatient settings, NCDP policy had little impact on the antibiotic prescription rate. Changes in antibiotic utilization rates were predominantly driven by non-NCDP varieties, particularly newer-generation antibiotics with enhanced therapeutic profiles. However, the policy more effectively facilitated the substitution of non-NCDP varieties with NCDP varieties in inpatient settings compared to outpatient settings. The overall and injectable antibiotic utilization rates remained withi

SUBMITTER: Lin F 

PROVIDER: S-EPMC12276250 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature