Comorbidity patterns and immune-metabolic differences in patients with acute-episode of schizophrenia spectrum disorders.

ABSTRACT: Patients with schizophrenia (SCZ) face multiple health challenges due to the complication of chronic diseases and psychiatric disorders. Among these, cardiovascular comorbidities are the leading cause of their life expectancy being 15-20 years shorter than that of the general population. Identifying comorbidity patterns and uncovering differences in immune and metabolic function are crucial steps toward improving prevention and management strategies. A retrospective cross-sectional study was conducted using electronic medical records of inpatients discharged between 2015 and 2024 from a municipal psychiatric hospital in China. The study included patients diagnosed with Schizophrenia, Schizotypal, and Delusional Disorders (SSDs) (ICD-10: F20-F29). Comorbidity patterns were identified throug

SUBMITTER: Wu G 

PROVIDER: S-EPMC12276266 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature