Endoscopic ultrasound-guided portosystemic pressure gradient measurement <i>vs.</i> transjugular balloon occlusion measurement in patients with cirrhosis (ENCOUNTER): A bicentric EU study.

ABSTRACT:

Background & aims

Patients with cirrhosis and portal hypertension are at increased risk of hepatic decompensation and liver-related mortality. While the hepatic venous pressure gradient (HVPG) is the accepted method for quantifying portal hypertension, its measurement and limited availability pose challenges. Endoscopic ultrasound-guided portal pressure gradient (EUS-PPG) provides a direct alternative. The ENCOUNTER study is the first to compare EUS-PPG to HVPG in the same patient, simultaneously.

Methods

This prospective, international, bicentric study included patients referred for HVPG or transjugular intrahepatic portosystemic shunt (TIPS) placement at the University Hospital of Leuven (Belgium) and Hospital Clinic Barcelona (Spain). Patients underwent standard-of-care H

SUBMITTER: Vanderschueren E 

PROVIDER: S-EPMC12276445 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature