Regional variations and trends in liver transplantation practices across Europe.

ABSTRACT:

Background & aims

Liver transplantation (LT) is a live-saving therapy for patients with end-stage liver disease, but demand exceeds supply, leading to waiting list (WL) mortality. This study reviews LT practices and trends in Europe to identify potential policies for improving outcomes.

Methods

Data were extracted from the European Liver Transplant Registry and the Global Observatory on Donation and Transplantation. Countries were categorized into Eastern (EEC), Mediterranean (MEC), and Northern European (NEC). We analyzed LT indications, recipient and donor age, transplant type, and WL outcomes from 2012 to 2022.

Results

Etiology of LT differed across regions: HBV cirrhosis predominated in EEC (37.3%), whereas alcohol-related liver disease was more frequent in NEC (4

SUBMITTER: Di Maira T 

PROVIDER: S-EPMC12276449 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature