Efficacy and Safety of Surgical Treatment Among Older Adult Patients (80 Years) With Pancreatic Cancer: A Systematic Review and Meta-Analysis.

ABSTRACT:

Background

With rapid population aging, the number of older adult patients presenting with pancreatic cancer is increasing. This meta-analysis aimed to clarify the efficacy and safety of surgical interventions for pancreatic cancer among older adult patients.

Methods

Literature published in PubMed, Cochrane Library, and ICHUSHI databases until January 2024 was systematically searched. Comparative studies reporting outcomes of pancreatic cancer resection among patients aged 80 years or older were included in the analysis. Fifteen retrospective studies involving 22 647 patients were included in the meta-analysis: 2930 patients aged 80 years or older who underwent pancreatic resection, 2059 patients aged 80 years or older treated with chemotherapy, and 17 658 patients under 80 

SUBMITTER: Ikenaga N 

PROVIDER: S-EPMC12276457 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature