Mortality and cardiovascular disease after cholecystectomy in type 2 diabetes: A nationwide longitudinal cohort study.

ABSTRACT:

Background

The long-term effects of cholecystectomy on mortality and cardiovascular disease (CVD) in patients with diabetes have not been evaluated. In the present study, we investigated the longitudinal effects of cholecystectomy on mortality and CVD in a population-based cohort with type 2 diabetes (T2D).

Methods

In total, 2 216 930 national health examination participants with T2D, including 19 258 patients with cholecystectomy, were followed up for a median of 7.9 years. The adjusted hazard ratios (aHRs) were calculated for all-cause mortality and CVD (myocardial infarction or ischemic stroke) in the cholecystectomy group compared with the nonoperative controls.

Results

The cholecystectomy group had a significantly higher risk of mortality than controls (aHR 1.10,

SUBMITTER: Jung HN 

PROVIDER: S-EPMC12276458 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature