Potential reduction of global colorectal cancer, 1990-2021.

ABSTRACT:

Objectives

Primary prevention targeting modifiable risk factors would reduce the global burden of colorectal cancer, but the quantitative results are uncertain. We aimed to assess the global burden of colorectal cancer attributed to modifiable lifestyle factors and quantify the potential increase in life expectancy resulting from the elimination of these risk factors.

Methods

Based on the Global Burden of Disease Study 2021, we examined colorectal cancer deaths and disability-adjusted life years attributed to modifiable risk factors (including smoking, diet low in whole grains, diet low in milk, diet high in red meat, diet low in calcium, diet high in processed meat, and diet low in fiber) at the global, regional, and national levels from 1990 to 2021. The abridged period li

SUBMITTER: Luo Z 

PROVIDER: S-EPMC12276565 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature