Limited association between multimorbidity and high-sensitive C-reactive protein or gait speed in community-dwelling octogenarians - findings from the BUTTERFLY study.

ABSTRACT:

Background

Biological age is a key determinant of disease progression and increased morbidity. However, it is unclear whether multimorbidity is associated with low-grade inflammation or gait speed in octogenarians.

Aim

To examine cross-sectional associations between commonly used comorbidity indices and either elevated high-sensitivity C-reactive protein (hsCRP) or reduced gait speed in community-dwelling non-frail adults aged 80 and older.

Methods

a total of 404 community-dwelling older adults (mean age: 83 ± 3 years) were assessed for multimorbidity, gait speed, and hscrp. five comorbidity indices were calculated: charlson comorbidity index, cumulative illness rating scale for geriatrics, elixhauser comorbidity index (eci), rockwood frailty index, and a weighted mod

SUBMITTER: Debain A 

PROVIDER: S-EPMC12276595 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature