China Multi-Center Cohort Study on Risk Evaluation of Arrhythmogenic Cardiomyopathy: The ChinaCORE ACM Registry.

ABSTRACT:

Background

Arrhythmogenic cardiomyopathy (ACM) patients in China exhibit unique genetic and clinical characteristics. There is a lack of prognostic models specific to Chinese ACM patients.

Objectives

This study aims to establish a large, national ACM patient cohort with uniformly collected, high-quality data for future risk prediction.

Methods

This study includes patients with definite or borderline ACM diagnoses, along with their genotype-positive relatives. At baseline, comprehensive data collection includes medical history, electrocardiograms, imaging data, genetic testing, and laboratory evaluations. Outcome data include heart failure events and malignant ventricular arrhythmias.

Results

As of September 2024, the registry has enrolled 622 participants, incl

SUBMITTER: Hu Y 

PROVIDER: S-EPMC12277196 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature