Position Statement on Antiplatelet Therapy for East Asians With Coronary Artery Disease: 2025 Update.

ABSTRACT: Growing clinical evidence has indicated that East Asian patients have a lower risk for cardiovascular events but a higher risk of serious bleeding during antiplatelet therapy compared with Western populations-referred to as the "East Asian Paradox." The unique risk-benefit tradeoff observed in East Asian populations has been a topic of interest, which may be influenced by a complex interplay of genetic and environmental risk factors-such as specific atherothrombotic cardiovascular risks, helicobacter pylori infection, sites of cranial atherosclerosis, and low body weight. There exist knowledge gaps in the antiplatelet therapy among East Asian populations with coronary artery disease, such as the individualized assessment of ischemic and bleeding risk, de-escalation strategy of dual antipla

SUBMITTER: Gong Y 

PROVIDER: S-EPMC12277199 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature