<i>Hypericum empetrifolium</i> subsp. <i>empetrifolium</i>: an assessment of its antifungal, antidiabetic, anti-aging, and neuroprotective potential.

ABSTRACT:

Introduction

Hypericum empetrifolium subsp. empetrifolium Willd. (Hypericaceae), traditionally used in folk medicine, was investigated for its diverse biological activities. The study was driven by the increasing global health and economic burden posed by fungal infections, highlighting the urgent need for novel antifungal agents.

Methods

Plant materials were collected from distinct regions in Türkiye. Methanolic extracts were prepared and tested in vitro for antimicrobial and enzyme inhibition activities. Minimum inhibitory concentration (MIC) and IC₅₀ values were determined using standard microdilution and spectrophotometric assays. Phytochemical profiling of the extracts was performed using HPLC-DAD and LC-HR/MS to identify major chemical constitu

SUBMITTER: Demirci Kayıran S 

PROVIDER: S-EPMC12277336 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature