Age-period-cohort analysis of syphilis epidemics in Eastern China, China, 2005-2024.

ABSTRACT:

Background

Syphilis remains one of the serious public health challenges in China and worldwide. This study aims to assess the potential independent risks associated with age, period, and birth cohort for the reported incidence of syphilis in Eastern China.

Methods

Data on all syphilis cases from 2005 to 2024 in Zhejiang Province in Eastern China were collected from the China Information System for Disease Control and Prevention. The Age-Period-Cohort (APC) model was used to analyze the effect coefficients, which were then converted into relative risks (RRs).

Results

From 2005 to 2024, a total of 617,097 syphilis cases were reported in Zhejiang Province. The reported incidence of syphilis decreased by an average of -3.53% per year across all age groups (95% CI: -4.34,

SUBMITTER: Ding Z 

PROVIDER: S-EPMC12277379 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature