Potential sustained production of polyhydroxyalkanoate copolymers using cyanobacteria microbiomes.

ABSTRACT: The copolymer poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) is considered one of the most promising PHA candidates for bioplastics production, exhibiting superior physical properties than the homopolymer poly(3-hydroxybutyrate) (PHB). In this study, for the first time, PHBV was successfully produced under non-sterile conditions with Synechocystis sp. and Synechococcus sp. as the dominant cyanobacteria in microbiomes. A semi-continuous cultivation approach was employed, alternating between growth and accumulation phases over an extended period of 56 days. The process included valerate supplementation as an external carbon precursor, and the working volume was 2.5 L. Additionally, four independent repetitions of PHBV production and recovery were conducted. This methodology contrasts wi

SUBMITTER: Sun L 

PROVIDER: S-EPMC12277418 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature