Gestational Diabetes Mellitus and Heart Failure: A Systematic Review and Meta-Analysis.

ABSTRACT:

Background

The extent of the association between gestational diabetes mellitus (GDM) and the incidence of heart failure (HF) largely remains unclear.

Objectives

The aim of the study was to synthesize the evidence on the association of GDM and risk of HF.

Methods

This study is a systematic review and meta-analysis. We searched PubMed and Embase through July 24, 2024, for cohort studies reporting on the GDM and HF association. We pooled adjusted relative risk (RR) estimates of the association of GDM and HF using a random-effects model meta-analysis.

Results

In a meta-analysis of 8 observational studies, a total of 6,371,877 participants (weighted averages-age: 28.7 years, 89.7% White, body mass index 25.6 kg/m², 310,351 with GDM) were assessed and expe

SUBMITTER: Broni EK 

PROVIDER: S-EPMC12277592 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature