Global burden of amputation among children and adolescents from 1990 to 2021: systematic analysis of the Global Burden of Disease study 2021.

ABSTRACT:

Introduction

Amputation among children and adolescents, with its substantial physical, psychological, and economic impacts, remains a significant global health issue.

Objectives

This study uses data from the Global Burden of Disease (GBD) to examine trends in amputation burden among youth aged 0-19 from 1990 to 2021.

Methods

This study utilized the 2021 GBD dataset, focusing on the incidence, prevalence, and years lived with disabilities (YLDs) associated with amputations. We applied pinpoint regression and age-period-cohort models to explore trends across the socio-demographic index (SDI) regions, GBD regions, and sex groups from 1990 to 2021, while also forecasting the burden of amputations up to 2040.

Results

We found a global decline in the age-standardized

SUBMITTER: Zhang T 

PROVIDER: S-EPMC12277607 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature