Mitral annular disjunction and mitral valve prolapse: long-term risk of ventricular arrhythmias after surgery.

ABSTRACT:

Background and aims

Mitral valve prolapse (MVP) is associated with progressive mitral regurgitation (MR) requiring surgical correction. A subset of patients with MVP experience ventricular arrhythmias (VA), and mitral annular disjunction (MAD) has been reported as a risk factor. This study aimed to assess the long-term risk of VA in patients with MAD and MVP undergoing mitral valve surgery for MR.

Methods

Patients with MVP with moderate or severe degenerative MR undergoing mitral valve surgery (repair or replacement) in 2010-22 at Karolinska University Hospital were included. Mitral annular disjunction length, referring to true MAD, was measured at end systole on pre- and post-operative transthoracic echocardiography. The primary outcome consisted of VA including hospitaliza

SUBMITTER: Lodin K 

PROVIDER: S-EPMC12277880 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature