Proteomic Investigation of Human Dental Pulp to Identify Individuals Who Are Pregnant.

ABSTRACT: Biomolecules preserved in dental pulp are increasingly being used to identify individuals in the context of forensics and archaeology. Despite the vast amount of research into host and pathogen DNA, the potential use of physiologically informative proteins preserved in dental pulp has rarely been studied. Here, we hypothesized that pregnancy-specific proteins circulating in the blood could be identified from the dental pulp of postpartum individuals and this was investigated using eight human third molars extracted from four postpartum and three control individuals during clinical treatment. A total of 885 proteins were identified from these eight dental pulp samples using liquid chromatography coupled tandem mass spectrometry, whose gene ontology compositions were similar to previous stud

SUBMITTER: Tsutaya T 

PROVIDER: S-EPMC12278038 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature