Comparing Venous vs. Capillary Blood Collection Methods for Proteomic Measurement in Peripheral Blood.

ABSTRACT:

Background

Capillary blood collection has a number of advantages over venous collection, especially in the context of increasing decentralized clinical trials and field-based testing. No studies are available comparing venous versus capillary blood collection for proteomics measurement. The aim of this study was to compare venous versus capillary blood collection methods for proteomic measurement in peripheral blood.

Methods

The expression of 368 different proteins from the Olink Explore 384 Inflammation panel was measured in both venous and capillary blood samples collected from 22 individuals at a single time point. Protein levels from venous and capillary blood samples were compared with descriptive statistics and correlation calculations. Correlations were examined for a

SUBMITTER: Ni Lochlainn M 

PROVIDER: S-EPMC12278044 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature