<i>Ruta montana</i> L. from Morocco: comprehensive phytochemical analysis and exploration of its antioxidant, antimicrobial, anti-inflammatory and analgesic properties.

ABSTRACT: Ruta montana L., a medicinal plant native to Morocco's Middle Atlas region, has been traditionally used for its therapeutic properties. This study aims to investigate its phytochemical composition and evaluate its biological and pharmacological activities, with a focus on its essential oil (EO) and phenolic extracts. The essential oil was extracted via hydrodistillation and analyzed using GC-MS to determine its chemical composition. Aqueous, hydro-ethanolic, and hydro-methanolic extracts were prepared and analyzed for their polyphenol, flavonoid, and tannin content using spectrophotometric methods and HPLC/UV ESI-MS. Antimicrobial activity was assessed using minimum inhibitory concentration (MIC) assays, while antioxidant potential was evaluated using the DPPH radical scavenging met

SUBMITTER: El Ouardi M 

PROVIDER: S-EPMC12278426 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature