Laser capture proteomics reveals new candidates for sperm-interacting proteins in the bovine oviduct epithelium.

ABSTRACT:

In brief

The molecular interactions between spermatozoa and the oviduct epithelium that are involved in capacitation and sperm availability during fertilization still remain largely unknown in many species. This study provides comprehensive proteomes of the apical and basal part of the bovine oviduct epithelium (isthmus and ampulla, pre- and post-ovulatory) and presents new protein candidates for sperm binding in the bovine functional sperm reservoir.

Abstract

The proximal region of the oviduct (isthmus) serves as a sperm reservoir in many mammalian species. This reservoir is composed of epithelial cells that bind sperm primarily to their apical cilia and ensure the survival of high-quality sperm until ovulation. The species-specific molecular interactions between spermatozo

SUBMITTER: Mahe C 

PROVIDER: S-EPMC12278443 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature