Multi-host distribution of Rhodococcus equi (Prescottella equi) strains and their phylogenomic clustering.

ABSTRACT:

Background

Rhodococcus equi is an intracellular bacterial pathogen that can cause infections in various hosts, including humans and animals. Host-associated virulence plasmids have been identified as key contributors to the pathogenicity of R. equi and potentially play a role in determining the host tropism of the bacteria. The investigation of additional clinical and environmental isolates is likely to provide novel insights into the population structure, infection pathways, and drug resistance of this important pathogen. We combined whole-genome sequencing and antimicrobial-susceptibility testing of 37 selected R. equi isolates from animal, human, and environmental sources, collected in Switzerland over a 21 year period. In addition, we gathered a total of 251 whole-genome sequen

SUBMITTER: Ghielmetti G 

PROVIDER: S-EPMC12278488 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature