Remnant cholesterol in early pregnancy as a predictor of gestational diabetes mellitus beyond triglyceride levels: a retrospective cohort study.

ABSTRACT:

Background

Recent findings suggest remnant cholesterol (RC) may contribute to gestational diabetes mellitus (GDM). This study aimed to explore the link between RC and GDM in early pregnancy to assess RC's risk independently of triglycerides (TG).

Methods

We performed a retrospective cohort study involving pregnant women admitted to the Suzhou Ninth Hospital affiliated to Soochow University. Data were obtained from the electronic medical record system. RC (mg/dL) was determined by subtracting high-density lipoprotein cholesterol and low-density lipoprotein cholesterol from total cholesterol. GDM was diagnosed using a 75-g oral glucose tolerance test diagnosed at 24-28 weeks of pregnancy. Various analyses, including logistic regressions, restricted cubic spline (RCS), subgroup

SUBMITTER: Li XX 

PROVIDER: S-EPMC12278675 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature