A highly effective curcumin analogue as "naked eye" colorimetric and fluorescent sensor for sensitive and selective detection of Hg²⁺ ions and its application on test strips and real sample analysis.

ABSTRACT: A thiophene appended curcumin-based colorimetric and fluorescent receptor (TAA) for selective recognition of Hg²⁺ ions was synthesized and characterized using ¹H NMR, ¹³C NMR and LC-MS spectroscopic techniques. TAA facilitates detection of Hg²⁺ by a "naked-eye" color change from yellow to colorless in visible light, and fluorescence 'turn-off' in UV light (365 nm). The observed fluorescence quenching is due to the chelation-enhanced fluorescence quenching (CHEQ). TAA exhibited excellent selectivity and sensitivity toward Hg²⁺ ions, even in the presence of competing cations. The binding constant (K _a) for Hg²⁺ ions was found to be 3.4 × 10⁵ M^-1, indicating a strong binding affinity. The

SUBMITTER: D K R 

PROVIDER: S-EPMC12278725 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature