Penalized distributed lag interaction model: Air pollution, birth weight, and neighborhood vulnerability.

ABSTRACT: Maternal exposure to air pollution during pregnancy has a substantial public health impact. Epidemiological evidence supports an association between maternal exposure to air pollution and low birth weight. A popular method to estimate this association while identifying windows of susceptibility is a distributed lag model (DLM), which regresses an outcome onto exposure history observed at multiple time points. However, the standard DLM framework does not allow for modification of the association between repeated measures of exposure and the outcome. We propose a distributed lag interaction model that allows modification of the exposure-time-response associations across individuals by including an interaction between a continuous modifying variable and the exposure history. Our model framewo

SUBMITTER: Demateis D 

PROVIDER: S-EPMC12278763 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature