Brachial-ankle pulse wave velocity predicts liver volume in patients with autosomal dominant polycystic kidney disease.

ABSTRACT:

Background

Autosomal dominant polycystic kidney disease (ADPKD) is the most common inherited kidney disease and Polycystic liver disease (PLD) is the most common extrarenal manifestation of ADPKD. Various non-inherited factors have been reported to affect total kidney volume (TKV) in ADPKD. However, the non-inherited factors affecting liver volume (LV) in ADPKD are unknown.

Methods

We aimed to identify the factors affecting LV and TKV in ADPKD; and to analyze the relationship between changes in these parameters and arterial stiffness, assessed using brachial-ankle pulse wave velocity (baPWV).

Results

We enrolled 165 patients (66 men and 99 women; mean age 47.3 ± 6.9 years). Univariable analysis revealed that sex, mean baPWV, ΔbaPWV, tolvaptan use, hyperlipidemia, hype

SUBMITTER: Tato W 

PROVIDER: S-EPMC12279127 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature