The effect of melatonin supplementation on glycemic control in patients with type 2 diabetes.

ABSTRACT:

Background and purpose

Melatonin supplementation has shown potential benefits in the management of diabetes in clinical trials; however, prior meta-analyses have not specifically focused on individuals with type 2 diabetes mellitus (T2DM). This study investigates the efficacy of melatonin supplementation in improving glycemic control among patients with T2DM by systematically reviewing and analyzing data from randomized controlled trials (RCTs).

Methods

A comprehensive literature search was conducted in PubMed, Cochrane Library, Scopus, Web of Science, and Embase from their inception to September 2024. RCTs evaluating the effects of melatonin supplementation in adults diagnosed with T2DM were included. The methodological quality of the studies was assessed using the Cochrane

SUBMITTER: Lv X 

PROVIDER: S-EPMC12279524 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature