Association between alpha-1-acid glycoprotein and frailty in US females aged 20-49 years: analysis of NHANES data (2015-2023).

ABSTRACT: As a significant global health issue, frailty has important implications for clinical practice and public health. Systemic inflammation has been identified as an important mechanism influencing the development of frailty. However, the potential impact of the inflammatory marker alpha-1-acid glycoprotein (AGP) on frailty is unclear. The aim of this study was to investigate the relationship between AGP levels and frailty. The present study employed a cross-sectional design and included a sample of 3802 females aged 20-49 years, drawn from the 2015-2023 National Health and Nutrition Examination Survey (NHANES) database. A weighted multivariate logistic regression was employed to construct a series of adjustment models, comprising crude, partial and fully adjusted models, with the objective of

SUBMITTER: Liu Y 

PROVIDER: S-EPMC12280186 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature