Clonal spread of bla_CTX-M-65 producing Salmonella enterica serovars detected in poultry retail meat in North Carolina, USA.

ABSTRACT: The rise of antimicrobial resistance (AMR) in Salmonella enterica poses a significant public health threat, particularly through the dissemination of extended-spectrum β-lactamase (ESBL) genes such as bla_CTX-M-65. This study investigated the prevalence, resistance profiles, and genomic characteristics of S. enterica isolates from retail poultry products in North Carolina, collected between 2020 and 2024. Among 132 isolates representing 25 serovars, 14 were identified as multidrug-resistant (MDR) strains harboring bla_CTX-M-65. Whole-genome sequencing revealed that these isolates belonged to three serovars-S. Infantis (n = 11), S. I -:r:1,5 (n = 2), and S. Senftenberg (n = 1)-with associated sequence types ST32 and ST14. Genomic analyses identified additional resistance

SUBMITTER: Monte DFM 

PROVIDER: S-EPMC12280192 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature