Association Between Statin Use in the Intensive Care Unit and Delirium in Patients Receiving Mechanical Ventilation: A Cross-Sectional Study.

ABSTRACT:

Background and aims

Delirium is a temporary cognitive dysfunction caused by organic factors. It is characterized by impaired attention and cognitive abilities. This condition is associated with a high prevalence of misdiagnosis and considerable risks of disability and mortality, particularly in intensive care unit (ICU) patients undergoing mechanical ventilation (MV). This study aimed to investigate the impact of the use of statins on the occurrence of delirium in patients undergoing MV in the ICU by applying a comprehensive data set.

Methods

The Medical Information Mart for Intensive Care-IV (MIMIC-IV) database was used for participant recruitment. The primary outcome was the prevalence of delirium. Secondary outcomes were the duration of ICU stay (DoIS) and duration of hos

SUBMITTER: Liu Z 

PROVIDER: S-EPMC12280229 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature