An unusual survival for 6.5 years with end-stage hepatitis C related advanced liver cirrhosis following sustained virologic response with direct antiviral agents - A case report from A low-resource setting.

ABSTRACT: Advanced chronic liver disease is frequently complicated by hepatic encephalopathy (HE), hepatorenal syndrome, and spontaneous bacterial peritonitis; predictors of poor prognosis that significantly reduce survival. While orthotopic liver transplantation (OLT) remains the definitive treatment, it is often inaccessible in resource-limited settings. We present the case of a 70-year-old retired hospital attendant with hypertension who developed decompensated liver cirrhosis secondary to chronic hepatitis C virus HCV infection. She presented with portal hypertension, grade 4 HE, hepatorenal syndrome, and spontaneous bacterial peritonitis. She remained in grade 3 to 4 HE for approximately three months and in grade 2-3 HE for an additional two months. Despite profound hepatic decompensation and a

SUBMITTER: Stephen RI 

PROVIDER: S-EPMC12280298 | biostudies-literature | 2025 Mar-Apr

REPOSITORIES: biostudies-literature