Hopelessness and Depression Predict Sarcopenia in Advanced CKD and Dialysis: A Multicenter Cohort Study.

ABSTRACT:

Background/objectives

Depression and hopelessness are frequently experienced in chronic kidney disease (CKD) and are generally associated with lessened physical activity. The aim of this study was to quantify the associations between sarcopenia as determined by SARC-F with both depression and hopelessness.

Design and setting

This multicenter cohort study involving cross-sectional and longitudinal analyses was conducted in a university hospital and four general hospitals, each with a nephrology center, in Japan.

Participants

Participants consisted of 314 CKD patients (mean age 67.6), some of whom were receiving dialysis (228, 73%).

Measurements

The main exposures were depression, measured using the Center for Epidemiologic Studies Depression (CES-D) questionnair

SUBMITTER: Kurita N 

PROVIDER: S-EPMC12280643 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature