Determinants of Post-Operative Cognitive Decline in Elderly People.

ABSTRACT:

Background

Surgery and anesthesia can result in temporary or permanent deterioration of the cognitive functions, for which causes remain unclear.

Objectives

In this pilot study, we analyzed the determinants of cognitive decline following a non-emergency elective prosthesis implantation surgery for hip or knee.

Design

Prospective single-center study investigating psychomotor response time and changes in MoCA scores between the day before (D-1) and 2 days after (D+2) following surgery at the Lariboisière Hospital (Paris, France).

Participants

60 patients (71.9±7.1-year-old, 72% women) were included.

Measurements

Collected data consisted in sociodemographic data, treatments, comorbidities and the type of anesthesia (local, general or both). Furthermore, we

SUBMITTER: Cartailler J 

PROVIDER: S-EPMC12280816 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature