Comparative transcriptome analysis reveals involvement of FOXL2 in regulation of ovulation cycle in chicken.

ABSTRACT: The egg-laying performance is closely related to ovulation of chicken. Ovulation is very complex and highly coordinated physiological process. However, little is known about the ovulation-related synergistic actions of molecules and their signaling. Here, we performed a comparative transcriptome analysis based on preovulatory, ovulatory, and post-ovulatory follicle data of thirty-week-old Lohmann Pink laying hens. Gene set enrichment analysis (GSEA) indicated that the ovulating follicles exhibited the significant changes in plasma membrane structure and cell morphology, and the immune response mediators and T-cells were activated in response to ovulation, and meanwhile multiple biological processes (such as oxidative phosphorylation and steroidogenesis) and biological functions of ribosome

SUBMITTER: Li X 

PROVIDER: S-EPMC12281005 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature