Lignin Dissolution and Direct Ultrasmall-Lignin-Nanoparticle Formation in Acidic and Alkaline Deep Eutectic Solvents: A Molecular-Level Insight.

ABSTRACT: Although deep eutectic solvents (DESs) have demonstrated significant potential in lignin processing, their influence on molecular stacking and conformational evolution during lignin dissolution and nanoparticle formation remains insufficiently understood. Here, we develop a green, straightforward, and single-step approach to produce self-assembled lignin nanoparticles (LNPs). The LNPs obtained using the acidic DES method exhibited a great size reduction, with an average size approximately one-ninth of that produced by conventional solvent-exchange methods. To gain mechanistic insights into the reconstruction, dissolution, and self-assembly of lignin in DESs, we integrate structural characterization with molecular dynamics simulations. Specifically, we simulate the dynamic behavior and conf

SUBMITTER: Yue X 

PROVIDER: S-EPMC12281085 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature