Unveiling Oral Health Impacts of Vaping in African Americans through Untargeted Metabolomics and Proteomics.

ABSTRACT: Electronic nicotine delivery systems (ENDSs), commonly termed e-cigarettes, have been advertised as a safer alternative to traditional tobacco cigarettes and promoted for smoking cessation. However, emerging evidence suggests a connection between e-cigarette use or vaping and an increased risk of oral disease, particularly among minoritized populations such as Black and African Americans (AAs). AA communities have historically experienced disproportionate harm from tobacco use, which could extend to vaping. In this study, we recruited 20 AAs and 28 individuals of other races, oversampled for vapers, with no statistical differences in age, sex, sugar intake, income, or education across groups. Whole saliva samples collected at the time of the visit were processed for untargeted UHPLC-ESI-MS

SUBMITTER: He X 

PROVIDER: S-EPMC12281207 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature