Structural Brain Correlates of Multidomain Resilience Among Youth Exposed to Neighborhood Disadvantage.

ABSTRACT:

Background

Many youth exposed to adversity exhibit resilience, yet the neurobiological factors that support resilience are poorly understood. Few studies have examined how brain structure is related to resilience across multiple domains of functioning.

Methods

We evaluated associations between brain structure (volume, thickness, surface area) and psychological, social, and academic resilience in a sample of 708 twins (7-19 years) exposed to neighborhood disadvantage from the Michigan Twin Neurogenetics Study, recruited from the Michigan State University Twin Registry.

Results

For youth exposed to neighborhood disadvantage, greater total gray matter volume predicted positive psychological adaptation, while smaller right caudal middle frontal gyrus surface area predicte

SUBMITTER: Suarez GL 

PROVIDER: S-EPMC12281360 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature