Treatment outcomes of extensively drug-resistant tuberculosis in Europe: a retrospective cohort study.

ABSTRACT:

Background

In 2021, World Health Organization revised of definition of extensive drug-resistant tuberculosis. We aimed to determine treatment outcomes of individuals affected by extensively drug-resistant tuberculosis in Europe.

Methods

This observational, retrospective cohort study included patients diagnosed with extensively drug-resistant tuberculosis in the World Health Organization European Region from 2017 to 2023. Participating centres collected consecutive, detailed individual data for extensively drug-resistant tuberculosis patients. Data were analysed with meta- and regression methods, accounting for between-country heterogeneity.

Findings

Among 11,003 patients with multidrug-resistant/rifampicin-resistant tuberculosis, 188 (1·7%) from 16 countries had exten

SUBMITTER: Kherabi Y 

PROVIDER: S-EPMC12281379 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature