Adaption of the Memorial Sloan Kettering Cancer Center Nomograms for the Prediction of Prostate Cancer-specific Death in Sweden: A Population-based Cohort Study.

ABSTRACT:

Background and objective

Prognostication is a cornerstone of the clinical management of prostate cancer. This study aims to update the pre- and postoperative Memorial Sloan Kettering Cancer Center (MSKCC) nomograms for the prediction of 10-yr prostate cancer-specific mortality in the competing risk setting in Sweden, and to evaluate the added value of comorbidities.

Methods

A cohort study was conducted including all men in the National Prostate Cancer Register of Sweden diagnosed with localised prostate cancer in 2007-2020, who underwent radical prostatectomy. Follow-up was until December 31, 2022. We used cause-specific Cox proportional hazard models to obtain the cumulative incidence of prostate cancer-specific and other-cause mortality. The models were validated in terms

SUBMITTER: Zelic R 

PROVIDER: S-EPMC12281531 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature