Global burden of esophageal diseases: a comprehensive analysis of disease trends and risk factors from 1990 to 2021.

ABSTRACT:

Background

Esophageal diseases (ED) are a common category of upper gastrointestinal disorders, mainly including gastroesophageal reflux disease (GERD), esophagitis, Barrett's esophagus, achalasia, and esophageal cancer (EC). In recent years, the high recurrence rate of GERD and poor prognosis of EC are paid more attention, collectively contributing to the global burden of ED.

Methods

For this study, we systematically analyzed the global distribution of ED from 1990 to 2021, detailing the burden across different countries, regions, and socio-demographic index (SDI) levels. Furthermore, we explored temporal trends in ED burden over this period and conducted decomposition analysis, health inequality analysis, and frontier analysis. Finally, we projected trends in ED burden from

SUBMITTER: Wei Y 

PROVIDER: S-EPMC12281767 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature