Minneola tangelo essential oil exhibits antibacterial activity against multidrug-resistant pathogens while maintaining cell safety.

ABSTRACT:

Background

The significant rise in antibiotic resistance has become an alarming situation urging the search for new antibacterial agents. Nature has always been a limitless source of bioactives with high safety profile. This study evaluates the antibacterial activity of essential oils from the leaves and fruit peels of Minneola tangelo cultivated in Egypt. In vitro cytotoxicity assay was conducted to ensure the safety profile of the active essential oils.

Methods

The antibacterial activity of clinical isolates of Acinetobacter baumannii and methicillin-resistant Staphylococcus aureus was assessed using the Kirby-Bauer disk diffusion method. Chemical profiling of the leaf and peel essential oils was performed using GC-MS. In vitro cytotoxicity assay of the leaf essential oil

SUBMITTER: Fahmy NM 

PROVIDER: S-EPMC12281854 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature