Expanding the cultivable human archaeome: <i>Methanobrevibacter intestini</i> sp. nov. and strain <i>Methanobrevibacter smithii</i> 'GRAZ-2' from human faeces.

ABSTRACT: Two mesophilic, hydrogenotrophic methanogens, WWM1085 and M. smithii GRAZ-2, were isolated from human faecal samples. WWM1085 was isolated from an individual in the United States and represents a novel species within the genus Methanobrevibacter. M. smithii GRAZ-2 (=DSM 116045) was retrieved from a faecal sample of a European, healthy woman and represents a novel strain within this species. Both Methanobrevibacter representatives form non-flagellated, short rods with variable morphologies and the capacity to form filaments. Both isolates showed the typical fluorescence of F₄₂₀ and methane production. Compared to M. smithii GRAZ-2, WWM1085 did not accumulate formate when grown with H₂ and CO₂. The optimal growth conditions were at

SUBMITTER: Weinberger V 

PROVIDER: S-EPMC12281867 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature