Immediate 2-Stage breast reconstruction outcomes after proton or photon postmastectomy radiotherapy.

ABSTRACT:

Purpose

To evaluate the impact of postmastectomy radiotherapy (PMRT) on immediate breast reconstruction (IBR) outcomes among patients treated with proton or photon radiotherapy.

Material and methods

Patients who had undergone mastectomy, immediate breast reconstruction, and PMRT at our institution were included in a retrospective analysis of risk factors for surgical site infection (SSI), unplanned reoperation, and reconstruction failure. Univariate Cox models were used to examine associations of variables with reconstruction outcomes.

Results

Two-hundred thirty-one women were included, of whom 224 (97.0 %) underwent two-stage IBR with placement of a tissue expander and 7 (3 %) had direct-to-implant IBR. One-hundred sixty-five patients (71.4 %) received proton and 65

SUBMITTER: Gao RW 

PROVIDER: S-EPMC12282210 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature