Pangenomics to understand prophage dynamics in the <i>Pectobacterium</i> genus and the radiating lineages of <i>Pectobacterium brasiliense</i>.

ABSTRACT: Bacterial pathogens of the genus Pectobacterium are responsible for soft-rot and blackleg diseases in a wide range of crops and have a global impact on food production. The emergence of new lineages and their competitive succession is frequently observed in Pectobacterium species, in particular in Pectobacterium brasiliense. With a focus on one such recently emerged P. brasiliense lineage in the Netherlands that causes blackleg in potatoes, we studied genome evolution in this genus using a reference-free graph-based pangenome approach. We clustered 1,977,865 proteins from 454 Pectobacterium spp. genomes into 30,156 homology groups. The Pectobacterium genus pangenome is open, and its growth is mainly contributed by the accessory genome. Bacte

SUBMITTER: Pardeshi LA 

PROVIDER: S-EPMC12282264 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature