Genomic analysis of <i>Legionella pneumophila</i> in the drinking water system of a large building over 25 years.

ABSTRACT: Legionella pneumophila, the causative agent of Legionnaires' disease, is often found in the plumbing systems of buildings, from where it can be transmitted to humans via inhalation or aspiration of contaminated water drops. Annual routine water sampling from the potable water system of an occupational healthcare building in Basel over 25 years was performed in accordance with national guidelines. Overall, 309 water samples were collected at 38 time points over the period of 25 years. L. pneumophila was recovered from 120 water samples (38.8%) from 26 time points. No clinical infections were recorded during this period. Initial decontamination measures were successful for ~12 years, after which an increase in the total number of Legionella c.f.u. as well as of L. pne

SUBMITTER: Seth-Smith HMB 

PROVIDER: S-EPMC12282300 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature