Characterization of a <i>Listeria monocytogenes</i> plasmid with antibiotic and stress resistance genes.

ABSTRACT: Listeriosis is a predominantly foodborne infection causing severe, invasive disease in the immunocompromised, with the causative agent being Listeria monocytogenes. While L. monocytogenes possesses innate resistance to several classes of antibiotics, acquired antibiotic resistance is low compared with other foodborne pathogens. Conversely, plasmids possessing stress tolerance mechanisms are common and contribute to their ability to persist in food production environments. However, very few have been identified, which also carry antibiotic resistance genes, particularly multidrug resistance regions. We scanned a UK collection of L. monocytogenes genomes and detected an isolate with the dfrD, lnuG and mphB genes, encoding predicted resistance to trim

SUBMITTER: Barker CR 

PROVIDER: S-EPMC12282311 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature