Decoding the virome reveals diverse novel viruses in tree shrews (Tupaia belangeri) in Yunnan Province.

ABSTRACT: Viruses circulating in small mammals possess the potential to infect humans. Tree shrews are a group of small mammals inhabiting widely in forests and plantations, but studies on viruses in tree shrews are quite limited. Herein, viral metagenomic sequencing was employed to detect the virome in the tissue and swab samples from seventy-six tree shrews that we collected in Yunnan Province. As the results, genomic fragments belonging to eighteen viral families were identified, thirteen of which contain mammalian viruses. Through polymerase chain reaction (PCR) and Sanger sequencing, twelve complete genomes were determined, including five parvoviruses, three torque teno viruses (TTVs), two adenoviruses, one pneumovirus, and one hepacivirus, together with three partial genomes, including two hep

SUBMITTER: Lian ZH 

PROVIDER: S-EPMC12282433 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature