Efficacy and Safety of Optic Nerve Sheath Fenestration for Idiopathic Intracranial Hypertension. A Subgroup-Focused Systematic Review and Meta-Analysis.

ABSTRACT:

Introduction

Optic nerve sheath fenestration (ONSF) is an important surgical management option for idiopathic intracranial hypertension (IIH) who failed medical treatment. We conducted a systematic review and meta-analysis to evaluate the outcomes of ONSF, with a focus to identify factors affecting treatment success.

Methods

A literature search was conducted up to December 2024. Primary outcomes included improvement in visual acuity, visual fields, and optic disc swelling resolution. We performed a detailed subgroup analysis based on geographic location, study design, surgical approach, and technical variations.

Results

Nineteen studies with a total of 1,159 patients were included in our study. ONSF significantly improved visual acuity in 34.5% (95% CI: 31.8-37.3%) an

SUBMITTER: Almasoud F 

PROVIDER: S-EPMC12282507 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature