Joint estimation of source dynamics and interactions from MEG data.

ABSTRACT: Current techniques to estimate directed functional connectivity from magnetoencephalography (MEG) signals involve two sequential steps: (a) estimation of the sources and their amplitude time series from the MEG data and (b) estimation of directed interactions between the source time series. However, such a sequential approach is not optimal as it leads to spurious connectivity due to spatial leakage. Here, we present an algorithm to jointly estimate the source and connectivity parameters using Bayesian filtering. We refer to this new algorithm as JEDI-MEG (Joint Estimation of source Dynamics and Interactions from MEG data). By formulating a state-space model for the locations and amplitudes of a given number of sources, we show that estimation of their connections can be reduced to a syste

SUBMITTER: Puthanmadam Subramaniyam N 

PROVIDER: S-EPMC12283153 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature