<i>Verrucomicrobium spinosum</i> essential genome and the divergence of cell division in the PVC superphylum.

ABSTRACT: The Planctomycetota-Chlamydiota-Verrucomicrobiota superphylum comprises bacteria with divergent traits, epitomizing the vast biodiversity of non-model organisms that remains unexplored. Among its members, Planctomycetota and Chlamydiota exhibit unique adaptations, including variations in peptidoglycan structure and cell division without FtsZ. Verrucomicrobiota represents the only name-giving phylum within the PVC not extensively investigated. Here, exhaustive transposon mutagenesis combined with massive sequencing reveal the essential genome of Verrucomicrobium spinosum. The essentiality report demonstrates that the dcw cluster is essential except mraW. Additionally, peptidoglycan analysis evidences that the composition and sac

SUBMITTER: Henriques V 

PROVIDER: S-EPMC12283558 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature