Dynamic trend analysis of global psoriasis burden from 1990 to 2021: a study of gender, age, and regional differences based on GBD 2021 data.

ABSTRACT:

Background

Psoriasis is a chronic immune-mediated skin disease associated with systemic comorbidities such as cardiovascular disease and depression. While genetic susceptibility, immune dysregulation, and environmental factors are known contributors, the precise etiology remains uncertain. This study uses data from the Global Burden of Disease (GBD 2021) database to examine global and regional trends in psoriasis incidence, prevalence, and disability-adjusted life years (DALYs), analyzing differences by gender, age, and region to guide public health planning.

Methods

Data from GBD 2021, covering 204 countries and regions, were used to estimate psoriasis incidence, prevalence, and DALYs through the DisMod-MR 2.1 model with Bayesian meta-regression to integrate multiple data s

SUBMITTER: Xiong J 

PROVIDER: S-EPMC12283580 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature